Welcome to the Website for Case Reports

About CARE

The CARE guidelines provide a framework that supports transparency and accuracy in the publication of case reports and the reporting of information from patient encounters. The acronym CARE was created from CA— the first two letters in case and RE—the first two letters in reports. The initial CARE tools are the CARE checklist and the Case Report Writing Templates; tools that support the writing of case reports and provide data that informs clinical practice guidelines and provides early signals of effectiveness, harms, and cost.

CITE the CARE Statement

If you are using the CARE Statement from this website, please cite a journal that published the CARE guidelines in 2013. Journal citations are available in the sidebar to the right. For example: Gagnier J, Kienle G, Altman DG, Moher D, Sox H, Riley DS, and the CARE group. The CARE guidelines: consensus-based clinical case report guideline development. Journal of Clinical Epidemiology;67(1),46-51.


Many people devoted time between 2011 and 2013 to the development of the CARE guidelines. Led by David Riley, Joel Gagnier, Gunver Kienle, and David Moher; the CARE group followed the process for guidelines development outlined on the Equator Network. This included (1) needs assessment, (2) literature reviews and interviews with experts to draft case report checklist items, (3) a meeting at the University of Michigan to draft consensus-based case report guidelines. And (4) the draft guidelines were pilot-tested, finalized, and published in 2013. We value your endorsement.

How will the CARE guidelines improve the transparency and accuracy of published case reports and how will this improve patient care? The publication of case reports following the CARE guidelines will provide practice-based data on interventions and outcomes that can be compared across therapeutic interventions and inform clinical practice guidelines. We believe this will improve patient care. The CARE guidelines are supported when medical journals, specialty organizations, and conferences:

  • Refer to the CARE guidelines and this website in publications and author guidelines,
  • Cite the CARE Statement,
  • Allow us to add their name to our list of CARE guideline endorsers, and
  • Bring the CARE Statement to the attention of the people with whom you work.


We welcome the opportunity to make the CARE guidelines and checklist available in different languages. Please see our translation policy at ‘About Case Reports’ for more information.


  • Patients: Case reports inform and expand therapeutic possibilities.
  • Clinicians: Case reports inform clinical practice and enhance critical thinking.
  • Researchers: Case reports generate hypotheses and inform clinical practice guidelines (CPGs).
  • Hospitals & Clinics: Case reports support peer review and quality assurance and inform CPGs.
  • Education: Case reports complement case-based learning and improve clinical reasoning.
  • Policy makers: Case reports facilitate the evaluation of clinical practice guidelines.
  • Healthcare Industry: Case reports support service innovation and post-marketing surveillance.


  • We work with healthcare stakeholders on case report projects such as (1) writing, training and publishing support, (2) web-based data collection, and (3) peer-review and quality assurance efforts.
  • We offer training and editorial services in writing, editing, and publishing case reports that follow the CARE guidelines for practitioners, academic institutions, specialty associations, and other healthcare stakeholders.


Email: dsrileymd@me.com; msbarber@integrativemed.org • Telephone: +505.690.0688

CARE Steering Committee: David Riley, Joel Gagnier, Gunver Kienle, David Moher, Gregory Plotnikoff, Larissa Shamseer and Melissa Barber.

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