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|Section||Item||Checklist item description||Reported on page|
|Title||1||The words “case report” and the area of focus should appear in the title (such as diabetes, a therapeutic approach, an outcome)|
|Key Words||2||2 to 5 key words that identify areas covered in this case report|
|Abstract||3a||Introduction—What is unique about this case? What does it add to the medical literature? Why is this important?|
|3b||The patient's main concerns and important clinical findings|
|3c||The main diagnoses, therapeutics interventions, and outcomes|
|3d||Conclusion—What are the “take-away” lessons from this case?|
|Introduction||4||One or two paragraphs summarizing why this case is unique with reference to the relevant medical literature|
|Patient Information||5a||De-identified demographic and other patient specific information|
|5b||Main concerns and symptoms of the patient|
|5c||Medical, family, and psychosocial history including relevant genetic information (this should also appear in the timeline)|
|5d||Relevant past interventions and their outcomes|
|Clinical Findings||6||Describe the relevant physical examination (PE) and other significant clinical findings|
|Timeline||7||Relevant data from the patient's history organized as a timeline|
|Diagnostic Assessment||8a||Diagnostic methods (PE, laboratory testing, imaging, surveys)|
|8b||Diagnostic challenges (access, financial, cultural)|
|8c||Diagnostic reasoning including other diagnoses considered|
|8d||Prognostic characteristics when applicable (staging)|
|Therapeutic Intervention||9a||Types of intervention (pharmacologic, surgical, preventive)|
|9b||Administration of intervention (dosage, strength, duration)|
|9c||Any changes in the interventions (with rationale)|
Follow-up and Outcomes
|10a||Clinician and patient-assessed outcomes (when appropriate)|
|10b||Important follow-up diagnostic and other test results|
|10c||Intervention adherence and tolerability (how was this assessed)|
|10d||Adverse and unanticipated events|
|Discussion||11a||Strengths and limitations in your approach to this case|
|11b||Discussion of the relevant medical literature|
|11c||The rationale for your conclusions (a causality assessment)|
|11d||The primary “take-away” lessons from this case report|
|Patient Perspective||12||When appropriate the patient should share their perspective on the treatments they received|
|Informed Consent||13||Did the patient give informed consent? Please provide if requested|
- Patients: Case reports inform and expand therapeutic possibilities.
- Clinicians: Case reports enhance critical thinking.
- Researchers: Case reports generate hypotheses.
- Hospitals & Clinics: Case reports support peer review and quality assurance evaluations.
- Education: Case reports improve clinical reasoning skills and support case-based learning.
- Policy makers: Case reports facilitate the evaluation of clinical practice guidelines.
- Healthcare Industry: Case reports support service innovation and post-marketing surveillance.
- We work with healthcare stakeholders on case report projects such as (1) writing, training and publishing support, (2) web-based data collection, and (3) peer-review and quality assurance efforts.
- We offer training and editorial services in writing, editing, and publishing case reports that follow the CARE guidelines for practitioners, academic institutions, specialty associations, and other healthcare stakeholders.
David Riley MD • 2437 NW Overton Street • Portland, OR 97210 • USA
Email: firstname.lastname@example.org; email@example.com • Telephone: +505.690.0688
CARE Steering Committee: David Riley, Joel Gagnier, Gunver Kienle, David Moher, Gregory Plotnikoff, Larissa Shamseer. Coordinator: Melissa Barber